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The research team’s studies received widespread attention after preclinical results showed that “certain cannabis extracts, including those high in cannabidiol (CBD), help prevent SARS-CoV-2 virus from entering cells and ward off cytokine storms that can lead to acute respiratory distress syndrome, ”explains the explanation.
The results were peer-reviewed which sparked questions and suggestions. Therefore, some experiments were repeated and additional studies were carried out. They were later published in the open access journal Aging. Details of the results are available in two studies: In Search of Prevention Strategies and Combating the Storm.
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Recognizing the need for large-scale validation, “The extracts of our most successful novel high-CBD C. sativa lines can be a useful and safe adjunct to COVID-19 prevention / treatment pending further investigation. “Noted the abstract of the study.
“Of all the cytokines, TNFα and IL-6 play a decisive role in the pathogenesis of the cytokine storm and are probably responsible for the escalation of the severity of the disease,” explains the summary of the second study. “Novel anti-TNFα and anti-IL-6 cannabis extracts may be useful additions to current anti-inflammatory therapies for treating COVID-19,” the study authors write.
Kovalchuk notes that the researchers reproduced the original results and that subsequent studies “further substantiated our original results”.
In continuation of their work on the effects of cannabis extracts with high CBD content on COVID-19, several additional papers on the results of the Kovalchuks are in progress.
“They see the potential for cannabis and hemp as a crop for farmers and for cannabis extracts, especially high-CBD cannabis, as additional therapies,” the university said in a statement.